Regulatory forum opinion piece: the role of the toxicologic pathologist in the postgenomic era: challenges and opportunities.

Regulatory forum opinion piece: the role of the toxicologic pathologist in the postgenomic era: challenges and opportunities.

The “omics,” high-throughput screening, computational modeling, and database mining revolutions have every arrived with euphoric expectations, appreciable hand waving, and guarantees to set toxicity testing priorities and scale back reliance on standard animal toxicity and carcinogenicity testing. Reflecting again on prior expertise with different predictive approaches and options, what follows the frenzy to endorse a […]

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What Is New about the Exposome? Exploring Scientific Change in Contemporary Epidemiology.

What Is New about the Exposome? Exploring Scientific Change in Contemporary Epidemiology.

On this commentary, I focus on the scientific modifications introduced by the exposome, asking what’s new about this method and line of analysis. I place the exposome in a historic perspective, by analyzing the circumstances below which the exposome has been conceived, developed and established within the context of latest epidemiological analysis. I argue that […]

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The application of omics in ruminant production: a review in the tropical and sub-tropical animal production context

The application of omics in ruminant production: a review in the tropical and sub-tropical animal production context

The demand for animal merchandise (e.g. dairy and beef) in tropical areas is predicted to extend in parallel with the general public demand for sustainable practices, attributable to components akin to inhabitants progress and local weather change. The need to extend animal manufacturing output should be achieved with higher administration and manufacturing applied sciences. For […]

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Integrating Genetic and Genomic Analyses of Combined Health Data Across Ecotypes to Improve Disease Resistance in Indigenous African Chickens

Integrating Genetic and Genomic Analyses of Combined Health Data Across Ecotypes to Improve Disease Resistance in Indigenous African Chickens

Poultry play an necessary function within the agriculture of many African international locations. The vast majority of chickens in sub-Saharan Africa are indigenous, raised in villages beneath semi-scavenging circumstances. Vaccinations and biosecurity measures hardly ever apply, and infectious illnesses stay a serious reason for mortality and diminished productiveness. Genomic choice for illness resistance gives a […]

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Comparative Genomics Reveals Novel Target Genes towards Specific Control of Plant-Parasitic Nematodes

Comparative Genomics Reveals Novel Target Genes towards Specific Control of Plant-Parasitic Nematodes

Plant-parasitic nematodes trigger intensive annual yield losses to worldwide agricultural manufacturing. Most cultivated vegetation haven’t any recognized resistance in opposition to nematodes and the few bearing a resistance gene may be overcome by sure species. Chemical strategies which were deployed to manage nematodes have largely been banned from use as a consequence of their poor […]

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Genomic evidence supporting the clonal expansion of extensively drug resistant tuberculosis bacteria belonging to a rare Proto - Beijing genotype

Genomic evidence supporting the clonal expansion of extensively drug resistant tuberculosis bacteria belonging to a rare Proto – Beijing genotype

Tuberculosis illness (TB), brought on by Mycobacterium tuberculosis, is a serious public well being concern in Thailand. The excessive prevalence of recent Beijing (Lineage 2.2.1) strains has been related to multi- and extensively-drug resistant infections (MDR-, XDR-TB), complicating illness management. The affect of rarer proto-Beijing (L2.1) strains is much less clear. In our research of thirty-seven […]

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