Genetic testing for BRCA1 and BRCA2 mutations
BRCAaccuTest ™ and BRCAaccuTest ™ PLUS are a reagent kit for producing libraries to analyze BRCA1 and BRCA2 genes using the next generation sequencing (NGS) method, which analyzes genomic DNA derived from blood or FFPE tissue.
- For patients with breast and ovarian cancer
- For HBOC (Hereditary Breast and Ovarian Cancer Syndrome) patients
- For family history or age of incidence of breast cancer
Specifications
Certification: CE-IVD
Target disease:
- Breast / ovarian cancer,
- HBOC (Hereditary Breast and Ovarian Cancer Syndrome)
Target enrichment method: Amplicon-based method
Quantity
- test 12 (6 + 6): (1 test each for DNA control)
- 24 tests: (1 test for DNA control)
Sample: Blood, FFPE tissue, tissue biopsy
Amount of input DNA: 10-30 ng
Target gene: BRCA1 / BRCA2
Target region: 22.4 kb (all protein-coding regions, splice regions, selected promoter, UTR, intron regions)
Amplicon: 160 (2 groups)
Hands-on time: > 5 hours
Variant type: SNV, In, Del, Dup, CNV *
NGS Platform and Reagent Kit: Illumina MiSeq, MiSeq Dx / MiSeq Reagent Nano, Micro kit, v2, 300 cycles
Sample Yield: Germline (11) / Somatic (5) Germline (23)
Analysis Solution: NGeneAnalySys ™ (CE)